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HPK1-IN-2

CAS No. 2056122-11-1

HPK1-IN-2( Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2 )

Catalog No. M23923 CAS No. 2056122-11-1

HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1;IC50<0.05 μΜ).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	219	In Stock
10MG	365	In Stock
25MG	608	In Stock
50MG	866	In Stock
100MG	1152	In Stock
500MG	2331	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

HPK1-IN-2
Note

Research use only, not for human use.
Brief Description

HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1;IC50<0.05 μΜ).
Description

HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1;IC50<0.05 μΜ). It also inhibits Lck (0.05 μΜ
In Vitro

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In Vivo

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Synonyms

Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2
Pathway

Angiogenesis
Target

FLT
Recptor

Flt3|HPK1|Lck
Research Area

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Indication

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Chemical Information

CAS Number

2056122-11-1
Formula Weight

380.47
Molecular Formula

C19H20N6OS
Purity

>98% (HPLC)
Solubility

H2O:25 mg/mL?(55.14 mM;?Need ultrasonic)
SMILES

O=C1C(C2=NC3=CC=C(N4CCN(C)CC4)C=C3N2)=C(N)C(C=CS5)=C5N1
Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Peter Brent Sampson, et al. Hpk1 inhibitors and methods of using same. WO2016205942A1.

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