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HOIPIN-1
CAS No. ——
HOIPIN-1( JTP-0819958 | HOIP inhibitor-1 )
Catalog No. M17007 CAS No. ——
HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameHOIPIN-1
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NoteResearch use only, not for human use.
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Brief DescriptionHOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM).
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DescriptionHOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway.
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In Vitro——
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In Vivo——
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SynonymsJTP-0819958 | HOIP inhibitor-1
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PathwayProteasome/Ubiquitin
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TargetE3 Ubiquitin Ligase
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RecptorE3 Ubiquitin Ligase
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight304.277
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Molecular FormulaC17H13NaO4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSodium (E)-2-(3-(2-methoxyphenyl)-3-oxoprop-1-en-1-yl)benzoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Katsuya K, et al. Biochem Biophys Res Commun. 2019 Jan 2. pii: S0006-291X(18)32846-8.
2. Katsuya K, et al. SLAS Discov. 2018 Dec;23(10):1018-1029.
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