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HMCEF

CAS No. 2002363-68-8

HMCEF( HMCEF )

Catalog No. M13124 CAS No. 2002363-68-8

A novel P-selectin inhibitor that directly binds to P-selectin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    HMCEF
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel P-selectin inhibitor that directly binds to P-selectin.
  • Description
    A novel P-selectin inhibitor that directly binds to P-selectin; intercalates into calf thymus DNA, cuts off DNA pBR22 and inhibits the proliferation of cancer cells; dose dependently inhibits inflammatory response of mice and inhibits thrombosis and inflammation, decreases serum TNFα and IL-8.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HMCEF
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Selectin
  • Recptor
    Selectin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2002363-68-8
  • Formula Weight
    389.455
  • Molecular Formula
    C23H23N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)[C@H](CC1=CC=CC=C1)NCCC2=NC(CO)=CC3=C2NC4=C3C=CC=C4
  • Chemical Name
    (2-(3-(hydroxymethyl)-9H-pyrido[3,4-b]indol-1-yl)ethyl)-L-phenylalanine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wu J, et al. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4631-6. 2. Wu J, et al. Drug Des Devel Ther. 2017 Jan 17;11:225-239.
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