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HG106

CAS No. 928712-10-1

HG106( —— )

Catalog No. M36018 CAS No. 928712-10-1

HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 88 In Stock
5MG 140 In Stock
10MG 227 In Stock
25MG 419 In Stock
50MG 604 In Stock
100MG 826 In Stock
500MG 1647 In Stock
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Biological Information

  • Product Name
    HG106
  • Note
    Research use only, not for human use.
  • Brief Description
    HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene.
  • Description
    HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis.HG106 can be used for the research of KRAS-mutant lung adenocarcinoma.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    928712-10-1
  • Formula Weight
    316.74
  • Molecular Formula
    C15H13ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (394.65 mM; Ultrasonic )
  • SMILES
    N(C(CCl)=O)C1=CC=2C(=NN(N2)C3=CC=C(OC)C=C3)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.?
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