HA-155

CAS No. 1229652-22-5

HA-155 ( Autotaxin Inhibitor IV )

Catalog No. M23406 CAS No. 1229652-22-5

HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 56 In Stock
5MG 119 In Stock
10MG 213 In Stock
25MG 511 In Stock
50MG 644 In Stock
100MG 786 In Stock
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Biological Information

  • Product Name
    HA-155
  • Note
    Research use only, not for human use.
  • Brief Description
    HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
  • Description
    HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
  • Synonyms
    Autotaxin Inhibitor IV
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    ATX (autotaxin)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1229652-22-5
  • Formula Weight
    463.3
  • Molecular Formula
    C24H19BFNO5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    B(C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\3/C(=O)N(C(=O)S3)CC4=CC=C(C=C4)F)(O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Albers H M H G , Hendrickx L J D , Van Tol R J P , et al. Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin[J]. Journal of Medicinal Chemistry, 2011, 54(13):4619-26.
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