Glycerophosphocholine
CAS No. 28319-77-9
Glycerophosphocholine ( Choline Alfoscerate; Alpha GPC; Choline glycerophosphate )
Catalog No. M18359 CAS No. 28319-77-9
Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
1G | 45 | In Stock |
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Biological Information
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Product NameGlycerophosphocholine
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NoteResearch use only, not for human use.
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Brief DescriptionGlycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia.
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DescriptionCholine Alfoscerate, also known as Alpha GPC and L-Alpha glycerylphosphorylcholine, is a component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. Choline Alfoscerate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. Choline Alfoscerate is used in the treatment of Alzheimer's Disease and other dementias.
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SynonymsCholine Alfoscerate; Alpha GPC; Choline glycerophosphate
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PathwayOthers
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TargetOther Targets
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RecptorAChE
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number28319-77-9
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Formula Weight257.22
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Molecular FormulaC8H20NO6P
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Purity98%
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SolubilityH2O : 500 mg/mL 1943.86 mM; DMSO : ≥ 125 mg/mL 485.97 mM
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SMILESC[N+](C)(C)CCOP(=O)([O-])OC[C@@H](CO)O
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Chemical Name(R)-2,3-dihydroxypropyl (2-(trimethylammonio)ethyl) phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Parnetti L, et al. Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation J Neurol Sci. 2007 Jun 15;257(1-2):264-9.
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