Gliquidone ( Gliquidone; Glurenorm; Beglynor; Glikvidon; Glycvidon )

Catalog No. M14125 CAS No. 33342-05-1

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HPLC

MSDS

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Product Name

Gliquidone
Note

Research use only, not for human use.
Brief Description

Gliquidone is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2.
Description

Gliquidone is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Synonyms

Gliquidone; Glurenorm; Beglynor; Glikvidon; Glycvidon
Pathway

Cell Cycle/DNA Damage
Target

Potassium Channel
Recptor

Potassium Channel
Research Area

Endocrinology
Indication

——

CAS Number

33342-05-1
Formula Weight

527.63
Molecular Formula

C27H33N3O6S
Purity

>98%(HPLC)
Solubility

Ethanol: 6 mg/mL (11.37 mM); DMSO: 105 mg/mL (199.0 mM)
SMILES

CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C
Chemical Name

1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

1.Angel I, et al. Fundam Clin Pharmacol, 1991, 5(2), 107-115.

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