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Glabridin

CAS No. 59870-68-7

Glabridin( Glabridin | Q-100692 | KB289522 | S-176045 )

Catalog No. M17552 CAS No. 59870-68-7

Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Glabridin
  • Note
    Research use only, not for human use.
  • Brief Description
    Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels.
  • Description
    Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Glabridin | Q-100692 | KB289522 | S-176045
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NMDAR
  • Recptor
    T1 tyrosinase| T3 tyrosinase
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    59870-68-7
  • Formula Weight
    324.37
  • Molecular Formula
    C20H20O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 150 mg/mL. 462.43 mM;
  • SMILES
    CC1(C=Cc2c(O1)ccc1c2OC[C@H](C1)c1c(cc(cc1)O)O)C
  • Chemical Name
    (R)-4-(8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yokota Tm , et al. Pigment Cell Res. 1998 Dec;11(6):355-61.
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