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Gefarnate

CAS No. 51-77-4

Gefarnate( —— )

Catalog No. M20591 CAS No. 51-77-4

Gefarnate is a synthetic compound used for the treatment of gastric ulcersand also used in the treatment of dry eye syndrome.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 68 In Stock
200MG 103 In Stock
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Biological Information

  • Product Name
    Gefarnate
  • Note
    Research use only, not for human use.
  • Brief Description
    Gefarnate is a synthetic compound used for the treatment of gastric ulcersand also used in the treatment of dry eye syndrome.
  • Description
    Gefarnate is a synthetic compound used for the treatment of gastric ulcersand also used in the treatment of dry eye syndrome.
  • In Vitro
    Gefarnate (0.001, 0.01, or 0.1 mg/mL) increases mucin-like glycoprotein secretion in a dose-dependent fashion, but the difference from the control is significant only at the concentration of 0.1 mg/mL. Gefarnate specifically stimulates the mucin-like glycoprotein secretion.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others
  • Indication
    Gastric and duodenal ulcers acute and chronic gastritis hyperacidity heartburn abdominal distension

Chemical Information

  • CAS Number
    51-77-4
  • Formula Weight
    400.64
  • Molecular Formula
    C27H44O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (249.60 mM)
  • SMILES
    CC(C)=CCC\C(C)=C\CC\C(C)=C\CCC(=O)OC\C=C(/C)CCC=C(C)C
  • Chemical Name
    [(2E)-37-Dimethylocta-26-dienyl] (4E8E)-5913-trimethyltetradeca-4812-trienoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dota A Takaoka-Shichijo Y Nakamura M . Gefarnate stimulates mucin-like glycoprotein secretion in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models[J]. Clinical ophthalmology (Auckland N.Z.) 2013 7(default):211-217.
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