Gadobutrol

Research use only, not for human use.

Gadobutrol is a nonionic paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI).

Gadobutrol is a nonionic paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI).(In Vitro):Gadobutrol leads to a gradual decrease in cell density with increasing concentration under neutron irradiation.(In Vivo):Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice.

Gadobutrol leads to a gradual decrease in cell density with increasing concentration under neutron irradiation. Cell Viability Assay Cell Line:Human melanoma cell line Sk-Mel-28 Concentration:0-30 mM Incubation Time:1 hour Result:Showed a decrease in cell density to 26% at 30 mM while to 80% with no gadobutrol under neutron irradiation.

Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice. Animal Model:Female C57BL/6 N mice, 11-13 weeks, 21-23 g)Dosage:200 mM Administration:Intravenous injection; once; a week Result:Enhanced cells signal in the habenula, hippocampal formation, and locus coeruleus.

ZK 135079

Others

Other Targets

Others

Neurological Disease

Neoplastic CNS Lesions

770691-21-9

604.71

C18H31GdN4O9

>98% (HPLC)

H2O:20 mg/mL (33.07 mM; Need ultrasonic)

OC[C@H](O)[C@@H]1CO[Gd]234567OC(=O)C[N]22CC[N]3(CC[N]14CC[N]5(CC2)CC(=O)O6)CC(=O)O7

——

(-20℃)

With Ice Pack

≥ 2 years