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GW6340

CAS No. 405910-78-3

GW6340( —— )

Catalog No. M36854 CAS No. 405910-78-3

GW6340 is a selective LXR agonist with potential anticancer activity that promotes macrophage reverse cholesterol transport (mRCT) and can be used to study atherosclerosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 125 In Stock
25MG 256 In Stock
50MG 430 In Stock
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Biological Information

  • Product Name
    GW6340
  • Note
    Research use only, not for human use.
  • Brief Description
    GW6340 is a selective LXR agonist with potential anticancer activity that promotes macrophage reverse cholesterol transport (mRCT) and can be used to study atherosclerosis.
  • Description
    GW6340 is an intestinal-specific LXR agonist. GW6340 promotes macrophage reverse cholesterol transport (mRCT).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Liver X Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    405910-78-3
  • Formula Weight
    581.07
  • Molecular Formula
    C33H32ClF3N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (172.10 mM; Ultrasonic )
  • SMILES
    O=C(N)CC=1C=CC=C(OCCCN(CC2=CC=CC(=C2Cl)C(F)(F)F)CC(C=3C=CC=CC3)C=4C=CC=CC4)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yasuda T, et al. Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo. Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):781-6.?
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