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Home - Products - GPCR/G Protein - Neuropeptide Y Receptor - GW438014A

GW438014A

CAS No. 469861-49-2

GW438014A( —— )

Catalog No. M33987 CAS No. 469861-49-2

GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 52 In Stock
5MG 76 In Stock
10MG 122 In Stock
25MG 242 In Stock
50MG 380 In Stock
100MG 531 In Stock
500MG 1143 In Stock
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Biological Information

  • Product Name
    GW438014A
  • Note
    Research use only, not for human use.
  • Brief Description
    GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
  • Description
    GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.
  • In Vitro
    ——
  • In Vivo
    Animal Model:obese ob/ob mice Dosage:10 mg/kg Administration:intraperitoneal injection; daily, for 7 d Result:Decreased the rate of weight gain in both lean and obese rats.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neuropeptide Y Receptor
  • Recptor
    Neuropeptide Y Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    469861-49-2
  • Formula Weight
    437.51
  • Molecular Formula
    C23H23N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (571.42 mM; Ultrasonic )
  • SMILES
    O=C(NC1=NC=2C=CC=CC2N1CCC=3C=CC=CC3)C=4C=CC=CC4.O=S(=O)(O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Daniels AJ, et, al. Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist. Regul Pept. 2002 Jun 15;106(1-3):47-54.?
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