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GSK329

CAS No. 1268490-12-5

GSK329( GSK-329 | GSK 329 )

Catalog No. M27768 CAS No. 1268490-12-5

GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GSK329
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
  • Description
    GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    GSK-329 | GSK 329
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    amyloid-β| Caspase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1268490-12-5
  • Formula Weight
    472.25
  • Molecular Formula
    C19H14Cl2F3N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (211.75 mM)
  • SMILES
    CNc1cc(Oc2c(Cl)cc(cc2Cl)N(C(N)=O)c2cccc(c2)C(F)(F)F)ncn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ju Wang, et al. Pharmacological inhibition of asparaginyl endopeptidase by δ-secretase inhibitor 11 mitigates Alzheimer’s disease-related pathologies in a senescence-accelerated mouse model. Translational Neurodegeneration volume 10, Article number: 12 (2021).
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