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GSK1904529A
CAS No. 1089283-49-7
GSK1904529A ( GSK-4529; GSK1904529a; GSK 1904529; GSK-1904529a )
Catalog No. M10341 CAS No. 1089283-49-7
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 69 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 178 | In Stock |
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| 50MG | 282 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK1904529A
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NoteResearch use only, not for human use.
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Brief DescriptionGSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM.
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DescriptionGSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, >100-fold more selective for IGF-1R/InsR than Akt1/2, Aurora A/B,B-Raf, CDK2, EGFR etc.
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SynonymsGSK-4529; GSK1904529a; GSK 1904529; GSK-1904529a
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PathwayAngiogenesis
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TargetIGF-1R
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RecptorIGF-1R; Insulin Receptor; B-Raf (V600E); Syk; VEGFR2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1089283-49-7
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Formula Weight851.96
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Molecular FormulaC44H47F2N9O5S
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Purity>98%(HPLC)
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SolubilityDMSO:124 mg/mL (145.54 mM); Ethanol:<1 mg/mL (<1 mM); Water：<1 mg/mL (<1 mM)
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SMILESO=C(NC1=C(F)C=CC=C1F)C2=CC(C3=C(C4=NC(NC5=CC(CC)=C(N6CCC(N7CCN(S(=O)(C)=O)CC7)CC6)C=C5OC)=NC=C4)N8C=CC=CC8=N3)=CC=C2OC
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Chemical NameN-(2,6-Difluorophenyl)-5-[3-[2-[[5-ethyl-2-(methyloxy)-4-[4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl]phenyl]amino]-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sabbatini P, et al. Clin Cancer Res, 2009, 15(9), 3058-3067.
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