GSK163090

CAS No. 844903-58-8

GSK163090 ( —— )

Catalog No. M24834 CAS No. 844903-58-8

GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 142 In Stock
10MG 242 In Stock
25MG 408 In Stock
50MG 599 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GSK163090
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
  • Description
    GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT1A;5-HT1B;5-HT1D;Dopamine
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    844903-58-8
  • Formula Weight
    415.5
  • Molecular Formula
    C25H29N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:14.29 mg/mL (34.39 mM; Need ultrasonic)
  • SMILES
    Cc1ccc(c(N2CCN(CCc3cccc(N(CCN4)C4=O)c3)CC2)ccc2)c2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Leslie CP, et al. Discovery of 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. J Med Chem. 2010 Dec 9;53(23):8228-8240.
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