
GSK-2881078
CAS No. 1539314-06-1
GSK-2881078( GSK2881078 | GSK 2881078 )
Catalog No. M12175 CAS No. 1539314-06-1
A potent and selective androgen receptor modulator (SARM) for the treatment of cachexia.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 58 | In Stock |
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10MG | 87 | In Stock |
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25MG | 192 | In Stock |
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50MG | 312 | In Stock |
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100MG | 520 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameGSK-2881078
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective androgen receptor modulator (SARM) for the treatment of cachexia.
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DescriptionA potent and selective androgen receptor modulator (SARM) for the treatment of cachexia.Other Indication Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsGSK2881078 | GSK 2881078
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogenReceptor
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number1539314-06-1
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Formula Weight330.3254
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Molecular FormulaC14H13F3N2O2S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 33 mg/mL
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SMILESN#CC1=C(C(F)(F)F)C2=C(N([C@H](C)CS(=O)(C)=O)CC2)C=C1
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Chemical Name1H-Indole-5-carbonitrile, 1-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-4-(trifluoromethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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UT-34
UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy. In LNCaP cells, UT-34 (3-10 μM; 24 hours) treatment inhibits the expression of PSA and FKBP5 and growth of LNCaP cells starting from 100 nM with maximum effect observed at 10 μM.
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Cortexolone 17 alpha...
Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist.
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Ailanthone
Ailanthone is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69?nM) and constitutively active truncated AR splice variants (IC50: 309?nM).