Cart
sales@molnova.com
GSK-25
CAS No. 874119-56-9
GSK-25( —— )
Catalog No. M17637 CAS No. 874119-56-9
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 76 | In Stock |
|
| 10MG | 107 | In Stock |
|
| 25MG | 162 | In Stock |
|
| 50MG | 257 | In Stock |
|
| 100MG | 430 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGSK-25
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
-
DescriptionGSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorRSK1| mTOR (p70S6K)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number874119-56-9
-
Formula Weight513.34
-
Molecular FormulaC24H16Cl2F2N6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (97.40 mM)
-
SMILESClc1nccc(c1)C=2NC(C)=C(C(N=2)c3ccc(Cl)cc3F)C(=O)Nc4cc5cnnc5cc4F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sehon CA, et al. J Med Chem. 2008 Nov 13;51(21):6631-4.
molnova catalog
related products
-
Fleroxacin
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
-
Methyl Undecenate
Methyl Undecenate is a fatty acid methyl ester of 10-undecenoic acid. It has a role as a metabolite.
-
Broxaldine
Broxaldine is a small molecular drug with antiprotozoal activity.
