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GS-143
CAS No. 916232-21-8
GS-143 ( GS 143; GS143 )
Catalog No. M24964 CAS No. 916232-21-8
GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 80 | In Stock |
|
| 10MG | 126 | In Stock |
|
| 25MG | 259 | In Stock |
|
| 50MG | 410 | In Stock |
|
| 100MG | 609 | In Stock |
|
| 500MG | 1287 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGS-143
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NoteResearch use only, not for human use.
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Brief DescriptionGS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.
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DescriptionGS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup-presses NF-κB acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect
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SynonymsGS 143; GS143
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PathwayOthers
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TargetOther Targets
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RecptorIκBα?phosphorylation
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Research Area——
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Indication——
Chemical Information
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CAS Number916232-21-8
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Formula Weight466.5
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Molecular FormulaC28H19FN2O4
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Purity>98% (HPLC)
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SolubilityDMSO:40 mg/mL?(85.75 mM;?Need ultrasonic)
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SMILESOC(c(cc1)ccc1N(C1=O)N=C(Cc2ccccc2)C1=Cc1ccc(-c(cccc2)c2F)o1)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rashmi BS, Gayathri D. Molecular characterization of gluten hydrolysing Bacillus sp. and their efficacy and biotherapeutic potential as probiotics using Caco-2 cell line. J Appl Microbiol. 2017 Sep;123(3):759-772. doi: 10.1111/jam.13517. Epub 2017 Aug 4. PubMed PMID: 28637081.
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