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GRP-60367

CAS No. 1309241-34-6

GRP-60367 ( —— )

Catalog No. M22631 CAS No. 1309241-34-6

GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GRP-60367
  • Note
    Research use only, not for human use.
  • Brief Description
    GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
  • Description
    GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RABV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1309241-34-6
  • Formula Weight
    353.46
  • Molecular Formula
    C21H27N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(C)c(OCCNC2CCN(CC2)C(=O)c2ccncc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pont V D , Wirblich C , Yoon J J , et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor[J]. Journal of Virology, 2020, 94(13).
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