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GPX4-IN-5
CAS No. 2922824-09-5
GPX4-IN-5( —— )
Catalog No. M37105 CAS No. 2922824-09-5
GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 96 | Get Quote |
|
| 5MG | 145 | Get Quote |
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| 10MG | 231 | Get Quote |
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| 25MG | 365 | Get Quote |
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| 50MG | 541 | Get Quote |
|
| 100MG | 767 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGPX4-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionGPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.
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DescriptionGPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM.GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGPX
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Research Area——
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Indication——
Chemical Information
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CAS Number2922824-09-5
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Formula Weight381.78
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Molecular FormulaC18H17ClFNO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (261.93 mM; Ultrasonic )
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SMILESO=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.
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