GPS491

CAS No. 2655502-29-5

GPS491( —— )

Catalog No. M35199 CAS No. 2655502-29-5

GPS491 has antiviral activity and inhibits HIV-1, adenovirus, and coronavirus replication by altering RNA processing.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 532 Get Quote
5MG 922 Get Quote
10MG 1140 Get Quote
25MG 1463 Get Quote
50MG 1822 Get Quote
100MG 2250 Get Quote
500MG 6264 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GPS491
  • Note
    Research use only, not for human use.
  • Brief Description
    GPS491 has antiviral activity and inhibits HIV-1, adenovirus, and coronavirus replication by altering RNA processing.
  • Description
    GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Antiviral
  • Recptor
    Antiviral | HIV Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2655502-29-5
  • Formula Weight
    397.32
  • Molecular Formula
    C13H5F6N3OS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=NC=2C=CC(=CC2S1)C(F)(F)F)C=3SC(=NC3)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zamiri M, et al. 2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing. ACS Med Chem Lett. 2021 Oct 29;12(11):1818-1823.?
molnova catalog
related products
  • Moroxydine hydrochlo...

    Moroxydine hydrochloride is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines. Structurally moroxydine is a heterocyclic biguanidine.

  • Tenofovir exalidex

    Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleoside/nucleotide analogs.

  • HBF-0259

    HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.