GNF179

CAS No. 1261114-01-5

GNF179 ( —— )

Catalog No. M23433 CAS No. 1261114-01-5

GNF179 is an optimized 8,8-dimethyl IP analog.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GNF179
  • Note
    Research use only, not for human use.
  • Brief Description
    GNF179 is an optimized 8,8-dimethyl IP analog.
  • Description
    GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1261114-01-5
  • Formula Weight
    427.9
  • Molecular Formula
    C22H23ClFN5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120 mg/mL (280.44 mM)
  • SMILES
    CC(C)(c1nc(-c(cc2)ccc2F)c(Nc(cc2)ccc2Cl)n1CC1)N1C(CN)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meister S, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science. 2011 Dec 9;334(6061):1372-7.
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