Cart
sales@molnova.com
GLPG-0492
CAS No. 1215085-92-9
GLPG-0492( GLPG0492 )
Catalog No. M10803 CAS No. 1215085-92-9
A novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 177 | In Stock |
|
| 5MG | 312 | In Stock |
|
| 10MG | 447 | In Stock |
|
| 25MG | 714 | In Stock |
|
| 50MG | 1017 | In Stock |
|
| 100MG | 1368 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGLPG-0492
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM.
-
DescriptionA novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM; exhibits anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate in a classical model of orchidectomized rat; shows a potential treatment for Duchenne muscular dystrophy (DMD).Other Indication Phase 1 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsGLPG0492
-
PathwayEndocrinology/Hormones
-
TargetAndrogen Receptor (AR)
-
RecptorAndrogen Receptor (AR)
-
Research AreaOther Indications
-
IndicationOther Disease
Chemical Information
-
CAS Number1215085-92-9
-
Formula Weight389.328
-
Molecular FormulaC19H14F3N3O3
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESN#CC1=CC=C(N(C(N(C)[C@]2(CO)C3=CC=CC=C3)=O)C2=O)C=C1C(F)(F)F
-
Chemical NameBenzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nique F, et al. J Med Chem. 2012 Oct 11;55(19):8236-47.
2. Cozzoli A, et al. Pharmacol Res. 2013 Jun;72:9-24.
molnova catalog
related products
-
2-hydroxy Flutamide
2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR)?for the treatment of prostate cancer.
-
S-23
S-23 is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.
-
CLP-3094
CLP-3094 is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GPR142 antagonist.
