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GLP-1R modulator C5

CAS No. 421578-93-0

GLP-1R modulator C5( —— )

Catalog No. M35562 CAS No. 421578-93-0

GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

GLP-1R modulator C5
Note

Research use only, not for human use.
Brief Description

GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.
Description

GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Glucagon Receptor
Recptor

Glucagon Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

421578-93-0
Formula Weight

371.43
Molecular Formula

C24H21NO3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (134.61 mM; Ultrasonic )
SMILES

OC1(CC(=O)c2ccccc2)C(=O)N(CCc2ccccc2)c2ccccc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452. ?

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