
GLN-1062
CAS No. 224169-27-1
GLN-1062( Memogain )
Catalog No. M26751 CAS No. 224169-27-1
GLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 140 | Get Quote |
![]() ![]() |
10MG | 222 | Get Quote |
![]() ![]() |
25MG | 448 | Get Quote |
![]() ![]() |
50MG | 653 | Get Quote |
![]() ![]() |
100MG | 888 | Get Quote |
![]() ![]() |
500MG | 1782 | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameGLN-1062
-
NoteResearch use only, not for human use.
-
Brief DescriptionGLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.
-
DescriptionGLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.(In Vivo):GLN-1062 has more than 15-fold higher bioavailability in the brain than the same doses of galantamine. In animal models of drug-induced amnesia, GLN-1062 produced several fold larger cognitive improvement than the same doses of galantamine, without exhibiting any significant levels of gastrointestinal side effects that are typical for the unmodified drug and other inhibitors of cholinesterases, such as donepezil and rivastigmin. In the ferret, dramatically reduced emetic and behavioral responses were observed when GLN-1062 was administered instead of galantamine.
-
In Vitro——
-
In Vivo——
-
SynonymsMemogain
-
PathwayOthers
-
TargetOther Targets
-
RecptorFarnesyl transferase (FTase)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number224169-27-1
-
Formula Weight391.467
-
Molecular FormulaC24H25NO4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (255.45 mM)
-
SMILES[H][C@]12C[C@@H](OC(=O)c3ccccc3)C=C[C@]11CCN(C)Cc3ccc(OC)c(O2)c13
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Stacy L Moulder, et al. A phase I open label study of the farnesyltransferase inhibitor CP-609,754 in patients with advanced malignant tumors. Clin Cancer Res. 2004 Nov 1;10(21):7127-35.
molnova catalog



related products
-
Alclometasone diprop...
Alclometasone dipropionate (Sch 22219) is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the study of skin inflammation.
-
Alisol C monoacetate
Alisol C 23-acetate is a natural product isolated from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration,has antibacterial activity.
-
Ghrelin (rat)
Endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.