Cart
sales@molnova.com
GA-017
CAS No. 2351906-74-4
GA-017( —— )
Catalog No. M35303 CAS No. 2351906-74-4
GA-017 is a potent, selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), exhibiting IC50 values of 4.10 and 3.92 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 176 | Get Quote |
|
| 5MG | 275 | Get Quote |
|
| 10MG | 425 | Get Quote |
|
| 25MG | 595 | Get Quote |
|
| 50MG | 908 | Get Quote |
|
| 100MG | 1197 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGA-017
-
NoteResearch use only, not for human use.
-
Brief DescriptionGA-017 is a potent, selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), exhibiting IC50 values of 4.10 and 3.92 nM, respectively.
-
DescriptionGA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2351906-74-4
-
Formula Weight343.38
-
Molecular FormulaC18H21N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20.83 mg/mL (60.66 mM; Ultrasonic (<80°C)
-
SMILESCC\C(=N\NC(=O)NCc1cccc(O)c1)c1ccc(O)c(C)c1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Aihara A, et al. Small molecule LATS kinase inhibitors block the Hippo signaling pathway and promote cell growth under 3D culture conditions. J Biol Chem. 2022 Apr;298(4):101779.?
molnova catalog
related products
-
Boldenone Cypionate
Boldenone Cypionate is an androgenic anabolic steroid used by recreational bodybuilders and regular gym members.
-
Benproperine phospha...
Benproperine phosphate is a cough suppressant.
-
NotoginsenosideFa
Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.
