Cart
sales@molnova.com
G6PDi-1
CAS No. ——
G6PDi-1( —— )
Catalog No. M22375 CAS No. ——
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 687 | In Stock |
|
| 10MG | 1147 | In Stock |
|
| 25MG | 1696 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameG6PDi-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionG6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?
-
DescriptionG6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes.?In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production.?In neutrophils, it suppresses respiratory burst.?
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorG6PD
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight284.34
-
Molecular FormulaC14H12N4OS
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C2CCCCc1nc(ncc12)Nc3cc(C#N)sc3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ghergurovich J M , Juan C. García-Caaveras, Wang J , et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway[J]. Nature Chemical Biology, 2020, 16(7):1-9.
molnova catalog
related products
-
AGI-14100
AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
-
CP-642931
CP-642931 (Sorbitol dehydrogenase-IN-1) is an orally active and highly potent sorbitol dehydrogenase inhibitor for the study of diabetes and cardiovascular disease.
-
IDH2R140Q-IN-2
IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.
