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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - G6PDi-1

G6PDi-1

CAS No.

G6PDi-1( —— )

Catalog No. M22375 CAS No.

G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    G6PDi-1
  • Note
    Research use only, not for human use.
  • Brief Description
    G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.
  • Description
    G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes.In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production.In neutrophils, it suppresses respiratory burst.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    G6PD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    284.34
  • Molecular Formula
    C14H12N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C2CCCCc1nc(ncc12)Nc3cc(C#N)sc3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ghergurovich J M , Juan C. García-Caaveras, Wang J , et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway[J]. Nature Chemical Biology, 2020, 16(7):1-9.
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