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Framycetin

CAS No. 119-04-0

Framycetin ( Fradiomycin B;Neomycin B )

Catalog No. M10654 CAS No. 119-04-0

An aminoglycoside antibiotic; selectively inhibits production of the mature miRNA, boosts a downstream protein, and inhibits invasion in HCC cell lines.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Framycetin
  • Note
    Research use only, not for human use.
  • Brief Description
    An aminoglycoside antibiotic; selectively inhibits production of the mature miRNA, boosts a downstream protein, and inhibits invasion in HCC cell lines.
  • Description
    An aminoglycoside antibiotic; selectively inhibits production of the mature miRNA, boosts a downstream protein, and inhibits invasion in HCC cell lines; a second-line agent for hepatic encephalopathy (HE) and bacterial infections due to cirrhosis.Bacterial Infection Approved
  • Synonyms
    Fradiomycin B;Neomycin B
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    119-04-0
  • Formula Weight
    614.64
  • Molecular Formula
    C23H46N6O13
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 60 mg/mL
  • SMILES
    OC[C@@H](O1)[C@@H](O[C@@H]2[C@H](N)[C@@H](O)[C@H](O)[C@H](CN)O2)[C@@H](O)[C@@H]1O[C@H]([C@@H](O)[C@H](N)C[C@@H]3N)[C@@H]3O[C@H]4O[C@H](CN)[C@H](O)[C@H](O)[C@H]4N
  • Chemical Name
    D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brinson RG, et al. Biochemistry. 2009 Jul 28;48(29):6988-97.
2. Childs-Disney JL, et al. ACS Chem Biol. 2016 Feb 19;11(2):375-80.
3. Bera S, et al. Molecules. 2012 Aug 2;17(8):9129-41.
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