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Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - Fmoc-Val-Cit-PAB-PNP

Fmoc-Val-Cit-PAB-PNP

CAS No. 863971-53-3

Fmoc-Val-Cit-PAB-PNP ( Fmoc-Val-Cit-PAB-PNP )

Catalog No. M16261 CAS No. 863971-53-3

A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-Val-Cit-PAB-PNP
  • Note
    Research use only, not for human use.
  • Brief Description
    A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).
  • Description
    A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).
  • Synonyms
    Fmoc-Val-Cit-PAB-PNP
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADCs Linker/Click Chemistry
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    863971-53-3
  • Formula Weight
    766.80
  • Molecular Formula
    C40H42N6O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 40 mg/mL
  • SMILES
    O=C(OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCC2C(C=CC=C3)=C3C4=C2C=CC=C4)=O)=O)=O)C=C1)OC5=CC=C([N+]([O-])=O)C=C5
  • Chemical Name
    L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69.
2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.
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