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Fmoc-Val-Ala-PAB

CAS No. 1394238-91-5

Fmoc-Val-Ala-PAB( Fmoc-Val-Ala-PAB | ACD linker | Fmoc-Val-Ala-PAB-OH )

Catalog No. M17993 CAS No. 1394238-91-5

Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-Val-Ala-PAB
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
  • Description
    Fmoc-Val-Ala-PAB, also known as Fmoc-Val-Ala-PAB-OH, is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vivo
    ——
  • Synonyms
    Fmoc-Val-Ala-PAB | ACD linker | Fmoc-Val-Ala-PAB-OH
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    ADCs Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1394238-91-5
  • Formula Weight
    515.61
  • Molecular Formula
    C30H33N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (64.64 mM)
  • SMILES
    O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](C(C)C)C(N[C@@H](C)C(NC4=CC=C(CO)C=C4)=O)=O
  • Chemical Name
    (9H-fluoren-9-yl)methyl (S)-1-((S)-1-(4-(hydroxymethyl)phenylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dal Corso, A., et al.Synthesis and Biological Evaluation of RGD Peptidomimetic–Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers，Chem. Eur. J., 21, 6921 (2015).
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