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Fluralaner

CAS No. 864731-61-3

Fluralaner ( AH252723;A1443 )

Catalog No. M20104 CAS No. 864731-61-3

Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 55 In Stock
25MG 87 In Stock
50MG 113 In Stock
100MG 186 In Stock
200MG 242 In Stock
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Biological Information

  • Product Name
    Fluralaner
  • Note
    Research use only not for human use.
  • Brief Description
    Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).
  • Description
    Fluralaner is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).
  • Synonyms
    AH252723;A1443
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    864731-61-3
  • Formula Weight
    556.29
  • Molecular Formula
    C22H17Cl2F6N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (179.76 mM);Water: Insoluble
  • SMILES
    Cc1cc(ccc1C(=O)NCC(=O)NCC(F)(F)F)C1=NOC(C1)(c1cc(Cl)cc(Cl)c1)C(F)(F)F
  • Chemical Name
    4-(5-(35-dichlorophenyl)-5-(trifluoromethyl)-45-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((222-trifluoroethyl)amino)ethyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ozoe Y et al. The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels. Biochem Biophys Res Commun. 2010 Jan 1;391(1):744-9.
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