Fletikumab( —— )

Catalog No. M36697 CAS No. 1357158-22-5

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Product Name

Fletikumab
Note

Research use only, not for human use.
Brief Description

Fletikumab (NNC0109-0012) is a monoclonal antibody that inhibits IL-20, primarily used in research on rheumatoid arthritis and psoriasis.
Description

Fletikumab (NNC0109-0012) is a monoclonal antibody targeting to IL-20. Fletikumab can be used for inflammation research, such as rheumatoid arthritis.
In Vitro

Fletikumab blocks IL-20 binding IL-20 receptor, acts potential function of inflammation inhibition.IL-20 is a member of IL-10 family, which includes IL-10, IL-19, IL-22, IL-24, IL-26, IL-28, and IL-29. IL-20 acts on renal cells and contributes to inflammation, fibrosis, and apoptosis through its receptors IL-20R1, IL-20R2, and IL-22R1.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Interleukin
Research Area

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Indication

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1. Kragstrup TW, et al. The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis. Front Immunol. 2018 Sep 25;9:2226.? ?

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