Fleroxacin

CAS No. 79660-72-3

Fleroxacin ( Fleroxacin, Quinodis, Megalocin, AM-833, Ro 236240 )

Catalog No. M19364 CAS No. 79660-72-3

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 37 In Stock
1G 59 In Stock

Biological Information

  • Product Name
    Fleroxacin
  • Note
    Research use only, not for human use.
  • Brief Description
    Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
  • Description
    Fleroxacin, a quinolone, is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV. Like other quinolones and fluoroquinolones the compound eradicates bacteria by interfering with DNA replication (bacterial DNA replication, transcription, repair and recombination). Fleroxacin is active against many Gram-positive and Gram-negative bacteria.
  • Synonyms
    Fleroxacin, Quinodis, Megalocin, AM-833, Ro 236240
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA gyrase; Topo II; Topo IV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    79660-72-3
  • Formula Weight
    369.34
  • Molecular Formula
    C17H18F3N3O3
  • Purity
    98%
  • Solubility
    DMSO : < 1 mg/mL
  • SMILES
    CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F
  • Chemical Name
    6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hussy P, et al. Antimicrob Agents ChemOthers. 1986 Jun;29(6):1073-8.
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