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Finasteride

CAS No. 98319-26-7

Finasteride( MK-906 | Propecia | Proscar )

Catalog No. M16893 CAS No. 98319-26-7

Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Finasteride
  • Note
    Research use only, not for human use.
  • Brief Description
    Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).
  • Description
    Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).(In Vitro):Finasteride (10 μM; 6-24 h) induces the expression of HO-1 and Nrf2 proteins in PC-3 cells.Finasteride decreases the conversion of [3H]testosterone (T) to [3H]dihydrotestosterone (DHT) in P. crustosum.(In Vivo):Finasteride (0.1-0.5 mg/kg; p.o. once daily for 16 weeks) reduces prostatic size in dogs with BPH without adversely affecting semen quality or serum testosterone concentration.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MK-906 | Propecia | Proscar
  • Pathway
    Endocrinology/Hormones
  • Target
    Reductase
  • Recptor
    5-α reductase
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    98319-26-7
  • Formula Weight
    372.55
  • Molecular Formula
    C23H36N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 75 mg/mL (201.32 mM); DMSO: 75 mg/mL (201.32 mM)
  • SMILES
    C[C@]12CC[C@H]3[C@@H](CC[C@@H]4[C@]3(C)C=CC(N4)=O)[C@@H]1CC[C@@H]2C(NC(C)(C)C)=O
  • Chemical Name
    (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Azzolina B, et al. J Steroid Biochem Mol Biol, 1997, 61(1-2), 55-64.
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