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Home - Products - Membrane Transporter/Ion Channel - Beta Amyloid - Fenlean

Fenlean

CAS No. 863193-70-8

Fenlean( —— )

Catalog No. M34597 CAS No. 863193-70-8

Fenlean (FLZ) is a tyrosine kinase Src inhibitor, a synthetic cyclic derivative of squamous amide from Annona glabra, with cytoprotective activity, which protects tyrosine hydroxylase function in a chronic MPTP/prostaglandin-type mouse model of Parkinson's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fenlean
  • Note
    Research use only, not for human use.
  • Brief Description
    Fenlean (FLZ) is a tyrosine kinase Src inhibitor, a synthetic cyclic derivative of squamous amide from Annona glabra, with cytoprotective activity, which protects tyrosine hydroxylase function in a chronic MPTP/prostaglandin-type mouse model of Parkinson's disease.
  • Description
    Fenlean, a natural squamosamide derivative, is a Src tyrosine kinase inhibitor. Fenlean can inhibit over-activated microglia and protect dopaminergic neurons. Fenlean can attenuate neuroinflammation in Parkinson's disease models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Beta Amyloid
  • Recptor
    Beta Amyloid | Src
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    863193-70-8
  • Formula Weight
    449.5
  • Molecular Formula
    C26H27NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NCCC1=CC=C(O)C=C1)C(=CC2=CC=C(O)C(OC)=C2)C3=CC(OC)=CC=C3OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tai W, et, al. Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models. Neuropharmacology. 2013 Dec;75:201-12. ?
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