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Fenlean
CAS No. 863193-70-8
Fenlean( —— )
Catalog No. M34597 CAS No. 863193-70-8
Fenlean (FLZ) is a tyrosine kinase Src inhibitor, a synthetic cyclic derivative of squamous amide from Annona glabra, with cytoprotective activity, which protects tyrosine hydroxylase function in a chronic MPTP/prostaglandin-type mouse model of Parkinson's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 181 | Get Quote |
|
| 5MG | 280 | Get Quote |
|
| 10MG | 519 | Get Quote |
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| 25MG | 908 | Get Quote |
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| 50MG | 1362 | Get Quote |
|
| 100MG | 1602 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFenlean
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NoteResearch use only, not for human use.
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Brief DescriptionFenlean (FLZ) is a tyrosine kinase Src inhibitor, a synthetic cyclic derivative of squamous amide from Annona glabra, with cytoprotective activity, which protects tyrosine hydroxylase function in a chronic MPTP/prostaglandin-type mouse model of Parkinson's disease.
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DescriptionFenlean, a natural squamosamide derivative, is a Src tyrosine kinase inhibitor. Fenlean can inhibit over-activated microglia and protect dopaminergic neurons. Fenlean can attenuate neuroinflammation in Parkinson's disease models.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptorBeta Amyloid | Src
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Research Area——
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Indication——
Chemical Information
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CAS Number863193-70-8
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Formula Weight449.5
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Molecular FormulaC26H27NO6
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCCC1=CC=C(O)C=C1)C(=CC2=CC=C(O)C(OC)=C2)C3=CC(OC)=CC=C3OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tai W, et, al. Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models. Neuropharmacology. 2013 Dec;75:201-12. ?
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