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FT-001
CAS No. 1778655-51-8
FT-001 ( FT001 )
Catalog No. M12678 CAS No. 1778655-51-8
FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 264 | Get Quote |
|
| 5MG | 403 | Get Quote |
|
| 10MG | 592 | Get Quote |
|
| 25MG | 888 | Get Quote |
|
| 50MG | 1242 | Get Quote |
|
| 100MG | 1701 | Get Quote |
|
| 500MG | 3402 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFT-001
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NoteResearch use only, not for human use.
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Brief DescriptionFT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1.
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DescriptionFT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model.
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SynonymsFT001
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number1778655-51-8
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Formula Weight467.58
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Molecular FormulaC25H29N3O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(N1[C@@H](C)CN(C(C2CC2)=O)C3=C1C=CC(C4=CC=C(N(CC5)CCS5(=O)=O)C=C4)=C3)=O
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Chemical Name(S)-1-(4-(cyclopropanecarbonyl)-6-(4-(1,1-dioxidothiomorpholino)phenyl)-2-methyl-3,4-dihydroquinoxalin-1(2H)-yl)ethan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Millan DS, et al. ACS Med Chem Lett. 2017 Jul 14;8(8):847-852.
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