FR901464

CAS No. 146478-72-0

FR901464( —— )

Catalog No. M34605 CAS No. 146478-72-0

FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 499 Get Quote
5MG 749 Get Quote
10MG 1064 Get Quote
25MG 1527 Get Quote
50MG 2052 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    FR901464
  • Note
    Research use only, not for human use.
  • Brief Description
    FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.
  • Description
    FR901464 is a potent spliceosome inhibitor with prominent anti-tumor and anti-cancer effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146478-72-0
  • Formula Weight
    507.62
  • Molecular Formula
    C27H41NO8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (197.00 mM; Ultrasonic )
  • SMILES
    C[C@H](OC(C)=O)\C=C/C(=O)N[C@@H]1C[C@H](C)[C@H](C\C=C(/C)\C=C\[C@H]2O[C@](C)(O)C[C@@]3(CO3)[C@@H]2O)O[C@@H]1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11.?
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