Cart
sales@molnova.com
FH535
CAS No. 108409-83-2
FH535( FH 535 | FH-535 )
Catalog No. M10331 CAS No. 108409-83-2
A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 47 | In Stock |
|
| 25MG | 86 | In Stock |
|
| 50MG | 150 | In Stock |
|
| 100MG | 259 | In Stock |
|
| 200MG | 383 | In Stock |
|
| 500MG | 619 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFH535
-
NoteResearch use only, not for human use.
-
Brief DescriptionA dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.
-
DescriptionA dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment; antagonizes β-catenin/Tcf–mediated transcription and inhibits the Wnt/β-catenin pathway; shows antiproliferation effect on transformed colon lung and liver cell lines.
-
In Vitro——
-
In Vivo——
-
SynonymsFH 535 | FH-535
-
PathwayWnt/Notch/Hedgehog
-
TargetBeta-catenin
-
RecptorPPARγ|PPARδ|Wnt/β-catenin
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number108409-83-2
-
Formula Weight361.2005
-
Molecular FormulaC13H10Cl2N2O4S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O
-
Chemical NameBenzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Handeli S, et al. Mol Cancer Ther. 2008 Mar;7(3):521-9.
2. Gedaly R, et al. PLoS One. 2014 Jun 18;9(6):e99272.
3. Su H, et al. J Transl Med. 2015 Mar 31;13:104.
molnova catalog
related products
-
iCRT-3
iCRT-3 is a selective, cell-permeable β-catenin responsive transcription (CRT) inhibitor with IC50 of 8.2 nM.
-
CCT-031374 hydrobrom...
A novel small-molecule Wnt signaling inhibitor that inhibits TCF-dependent transcription with IC50 of 6.1 uM in 7dF3 reporter assay.
-
β-catenin-IN-11a
β-catenin-IN-11a is a β-catenin/CD44/Nanog axis inhibitor, docks into the β-catenin allosteric site and interferes β-catenin/TCF-4 complex.
