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FGFR4-IN-1

CAS No. 1708971-72-5

FGFR4-IN-1( —— )

Catalog No. M23769 CAS No. 1708971-72-5

FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

FGFR4-IN-1
Note

Research use only, not for human use.
Brief Description

FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
Description

FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
In Vitro

FGFR4-IN-1 significantly inhibits the proliferation of HuH-7 hepatocellular carcinoma cells with IC50 of 7.8 nM.
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

FGFR
Recptor

FGFR4
Research Area

——
Indication

——

Chemical Information

CAS Number

1708971-72-5
Formula Weight

493.52
Molecular Formula

C24H27N7O5
Purity

>98% (HPLC)
Solubility

DMSO:6 mg/mL (12.16 mM; Need warming)
SMILES

COCCNc1cc(NC(N2c3nc(C=O)c(CN(CCOC4)C4=O)cc3CCC2)=O)ncc1C#N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO 2015059668 A1

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