FDI-6
CAS No. 313380-27-7
FDI-6( FDI-6 | FDI 6 | FDI6 | NCGC00099374 )
Catalog No. M17474 CAS No. 313380-27-7
FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
|
| 5MG | 68 | In Stock |
|
| 10MG | 129 | In Stock |
|
| 25MG | 214 | In Stock |
|
| 50MG | 289 | In Stock |
|
| 100MG | 429 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFDI-6
-
NoteResearch use only, not for human use.
-
Brief DescriptionFDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
-
DescriptionFDI-6 is an inhibitor of FOXM1 that block DNA binding. It act by specifically downregulating FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR.
-
In Vitro——
-
In Vivo——
-
SynonymsFDI-6 | FDI 6 | FDI6 | NCGC00099374
-
PathwayEndocrinology/Hormones
-
TargetOpioid Receptor
-
RecptorFOXM1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number313380-27-7
-
Formula Weight437.43
-
Molecular FormulaC19H11F4N3OS2
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 50 mg/mL; 114.30 mM
-
SMILESC1=CSC(=C1)C2=NC3=C(C(=C2)C(F)(F)F)C(=C(S3)C(=O)NC4=CC=C(C=C4)F)N
-
Chemical Name3-Amino-N-(4-fluorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gormally MV., et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165.
molnova catalog
related products
-
Nociceptin (1-13), a...
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.
-
[D-Ala2]leucine-enke...
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
-
Endomorphin 2?
Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX which was reversed by the MOR antagonist CTOP.??
Cart
sales@molnova.com