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FAUC-365
CAS No. 474432-66-1
FAUC-365( FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide )
Catalog No. M27448 CAS No. 474432-66-1
FAUC-365 is a D3 dopamine receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 102 | Get Quote |
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| 10MG | 155 | Get Quote |
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| 25MG | 305 | Get Quote |
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| 50MG | 484 | Get Quote |
|
| 100MG | 700 | Get Quote |
|
| 500MG | 1458 | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFAUC-365
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NoteResearch use only, not for human use.
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Brief DescriptionFAUC-365 is a D3 dopamine receptor agonist.
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DescriptionFAUC-365 is a D3 dopamine receptor agonist.(In Vitro):As a dichloro derivative, FAUC-365 revealed D3 affinities that were comparable to its methoxy-substituted analogs, however, the selectivities of FAUC-365 against 5HT-1A, 5-HT2, and R1 were substantially higher, which was demonstrated by the extraordinary selectivity ratios of 17600, 7200, 5200, and 680 over D1, D2long, D2short, and D4, respectively, were determined for FAUC-365 with Ki of 0.50 nM. In addition, the benzothiophene analog FAUC 346 and its oxa analog showed partial agonist character with EC50 values at 0.36 and 1.5 nM, respectively .
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In Vitro——
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In Vivo——
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SynonymsFAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorLOXL2|LOXL3
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Research Area——
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Indication——
Chemical Information
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CAS Number474432-66-1
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Formula Weight462.43
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Molecular FormulaC23H25Cl2N3OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (72.07 mM)
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SMILESClc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4s3)CC2)c1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Findlay AD,et al. Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3. J Med Chem. 2019 Nov 14;62(21):9874-9889.
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