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FATP1-IN-2

CAS No. 2650944-83-3

FATP1-IN-2( —— )

Catalog No. M35196 CAS No. 2650944-83-3

FATP1-IN-2 is a fatty acid transporter protein 1 (FATP1) inhibitor with oral activity for the study of obesity and metabolic diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    FATP1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    FATP1-IN-2 is a fatty acid transporter protein 1 (FATP1) inhibitor with oral activity for the study of obesity and metabolic diseases.
  • Description
    FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Mice Dosage:10 mg/kg Administration:P.o.Result:Showed a Cmax value above the mouse IC50 value.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2650944-83-3
  • Formula Weight
    353.39
  • Molecular Formula
    C19H20FN5O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (282.97 mM; Ultrasonic )
  • SMILES
    Cc1nc2ccccn2c1C(=O)CN1CCN(CC1)c1ccc(F)cn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565.?
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