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FAK-IN-14

CAS No. 2766666-22-0

FAK-IN-14( —— )

Catalog No. M37125 CAS No. 2766666-22-0

FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 67 Get Quote
5MG 93 Get Quote
10MG 155 Get Quote
25MG 254 Get Quote
50MG 365 Get Quote
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Biological Information

  • Product Name
    FAK-IN-14
  • Note
    Research use only, not for human use.
  • Brief Description
    FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.
  • Description
    FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    FAK
  • Recptor
    FAK | FGFR | PYK2 | mTOR | MEK | Akt | c-Kit
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2766666-22-0
  • Formula Weight
    502.43
  • Molecular Formula
    C21H24BrN7OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC)C=1SC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)N4CCN(C)CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.?
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