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F16

CAS No. 36098-33-6

F16 ( (E)-4-(3-indolylvinyl)-N-methylpyridinium iodide )

Catalog No. M26683 CAS No. 36098-33-6

F16 inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    F16
  • Note
    Research use only, not for human use.
  • Brief Description
    F16 inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.
  • Description
    F16 inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.(In Vitro):F16 arrests the cell cycle and increases apoptosis in F16-sensitive EpH4-A6 cells. F16 (3 μM) influences growth in human and mice cancer cell lines. F16 shows mitochondriotoxic property and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell.
  • Synonyms
    (E)-4-(3-indolylvinyl)-N-methylpyridinium iodide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IGF-1R; P-Akt (S473); P-Akt (T308); S6 Kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    36098-33-6
  • Formula Weight
    362.2
  • Molecular Formula
    C16H15IN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [I-].C[n+]1ccc(\C=C\c2c[nH]c3ccccc23)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang X, et al. Diffusion basis spectrum imaging detects and distinguishes coexisting subclinical inflammation, demyelination and axonal injury in experimental autoimmune encephalomyelitis mice. NMR Biomed. 2014 Jul;27(7):843-52.
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