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Home - Products - GPCR/G Protein - Antibacterial - F1063-0967

F1063-0967

CAS No. 613225-56-2

F1063-0967( F1063-0967 )

Catalog No. M18899 CAS No. 613225-56-2

F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    F1063-0967
  • Note
    Research use only, not for human use.
  • Brief Description
    F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
  • Description
    F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
  • In Vitro
    F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. At concentration above 0.1 μM, F1063-0967 remarkably induces IMR32 cell apoptosis. F1063-0967 induces apoptosis in IMR-32 cell line with an IC50 value of 4.13 μM. F1063-0967 has no effect on HL7702 cell line, and little inhibition effect on SH-SY5Y cell line.
  • In Vivo
    ——
  • Synonyms
    F1063-0967
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    DUSP26
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    613225-56-2
  • Formula Weight
    484.59
  • Molecular Formula
    C24H24N2O5S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 125 mg/mL 257.95 mM
  • SMILES
    S=C3S\C(=C/c1ccc(C)cc1)C(=O)N3CCCCCC(=O)Nc2ccc(C(=O)O)c(O)c2
  • Chemical Name
    (Z)-2-Hydroxy-4-{6-[5-(4-methyl-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-hexanoylamino}-benzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ren JX, et al. Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking. Biomed Pharmacother. 2017 May;89:376-385.
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