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F-11440
CAS No. 179756-58-2
F-11440 ( Eptapirone )
Catalog No. M12716 CAS No. 179756-58-2
A potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 76 | In Stock |
|
| 10MG | 129 | In Stock |
|
| 25MG | 255 | In Stock |
|
| 50MG | 473 | In Stock |
|
| 100MG | 673 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameF-11440
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33.
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DescriptionA potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33; shows ≥shows 100-fold higher affinity for the other serotonin receptor subtypes, and has no detectable antidopaminergic activity and antihistaminergic activity; decreases the forskolin-induced increase in AMP in HeLa cells expressing human 5-HT1A receptors; produces anxiolytic- and antidepressant-like effects in animal models.Anxiety Phase 1 Discontinued
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SynonymsEptapirone
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT1A
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number179756-58-2
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Formula Weight345.40
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Molecular FormulaC16H23N7O2
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Purity>98% (HPLC)
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SolubilityDMSO: 6 mg/mL (Need ultrasonic)
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SMILESO=C(N1C)N(CCCCN2CCN(C3=NC=CC=N3)CC2)N=CC1=O
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Chemical Name1,2,4-Triazine-3,5(2H,4H)-dione, 4-methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Koek W, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):266-83.
2. Prinssen EP, et al. Eur J Pharmacol. 2002 Oct 25;453(2-3):217-21.
3. Pauwels PJ, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.
2. Prinssen EP, et al. Eur J Pharmacol. 2002 Oct 25;453(2-3):217-21.
3. Pauwels PJ, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.
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