Cart
sales@molnova.com
Exo1
CAS No. 75541-83-2
Exo1( Exo-1 | Exo 1 | Exo1 )
Catalog No. M19078 CAS No. 75541-83-2
Exo1 is a chemical inhibitor of the exocytic pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 39 | In Stock |
|
| 50MG | 143 | In Stock |
|
| 100MG | 215 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameExo1
-
NoteResearch use only, not for human use.
-
Brief DescriptionExo1 is a chemical inhibitor of the exocytic pathway.
-
DescriptionExo-1 is a reversible inhibitor of exocytosis, activating Golgi ARF 1 (ADP-Ribosylation Factor) GTPase..
-
In VitroExo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.
-
In Vivo——
-
SynonymsExo-1 | Exo 1 | Exo1
-
PathwayOthers
-
TargetOther Targets
-
Recptorothers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number75541-83-2
-
Formula Weight273.26
-
Molecular FormulaC15H12FNO3
-
Purity>98% (HPLC)
-
SolubilityDMSO : 25 mg/mL 91.49 mM; H2O : < 0.1 mg/mL
-
SMILESCOC(=O)c1ccccc1NC(=O)c1ccc(F)cc1
-
Chemical Name2-(4-Fluorobenzoylamino)benzoic acid methyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Feng Y, et al. Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6469-74.
molnova catalog
related products
-
Esculentoside B
Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transformation.
-
Pinostrobin chalcone
Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 colon cancer cell line.
-
Kuwanon E
Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively.
