Evodiamine ( Evodiamine; Q-100579; Q100579; SC16015; SC 16015 )

Catalog No. M18707 CAS No. 518-17-2

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Product Name

Evodiamine
Note

Research use only, not for human use.
Brief Description

Evodiamine, an indole alkaloid found in Evodia rutaescarpa, acts as an anti-inflammatory compound.
Description

d-Evodiamine is a topoisomerase I and II inhibitor found in the fruit of Evodia rutaecarpa Bentham (Rutaceae). It displays a wide variety of biological activities, including enhancing TRAIL-induced apoptosis in bladder cancer cells, inducing cell cycle arrest in leukemia cells, improving glucose tolerance, and inhibiting viral replication of influenza virus.
Synonyms

Evodiamine; Q-100579; Q100579; SC16015; SC 16015
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

PGE
Research Area

Others-Field
Indication

——

CAS Number

518-17-2
Formula Weight

303.35
Molecular Formula

C19H17N3O
Purity

98%
Solubility

DMSO : ≥ 37 mg/mL; 121.97 mM
SMILES

CN1[C@@H]2c3c(CCN2C(=O)c2ccccc12)c1ccccc1[nH]3
Chemical Name

(S)-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

1. Lee TJ, et al. Mol Y Ther, 2006, 5(9), 2398-407.

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