
Etonogestrel
CAS No. 54048-10-1
Etonogestrel( ORG 3236 | 3-keto Desogestrel | 3-oxo Desogestrel )
Catalog No. M14929 CAS No. 54048-10-1
Etonogestrel is a steroidal progestin used in hormonal contraceptives.
Purity : >98% (HPLC)






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5MG | 45 | In Stock |
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50MG | 293 | In Stock |
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100MG | 435 | In Stock |
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Biological Information
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Product NameEtonogestrel
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NoteResearch use only, not for human use.
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Brief DescriptionEtonogestrel is a steroidal progestin used in hormonal contraceptives.
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DescriptionEtonogestrel is a steroidal progestin used in hormonal contraceptives.(In Vitro):Etonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium.Etonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system.Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).
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In VitroEtonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium.Etonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system.Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs). Western Blot AnalysisCell Line:Human endometrial stromal cells (HESCs) Concentration:100 nM Incubation Time:24 hoursResult:Increased FKBP51 mRNA and protein levels.
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In Vivo——
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SynonymsORG 3236 | 3-keto Desogestrel | 3-oxo Desogestrel
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorER
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number54048-10-1
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Formula Weight324.46
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Molecular FormulaC22H28O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34
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Chemical Name(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.McNicholas C, et al. Obstet Gynecol. 2015 Mar;125(3):599-604.
molnova catalog



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