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Etodolac
CAS No. 41340-25-4
Etodolac ( AY 24236; (±)-Etodolac; NIH 9918; NSC 282126 )
Catalog No. M14415 CAS No. 41340-25-4
A nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 31 | In Stock |
|
| 50MG | 43 | In Stock |
|
| 100MG | 61 | In Stock |
|
| 200MG | 87 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEtodolac
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NoteResearch use only, not for human use.
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Brief DescriptionA nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM.
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DescriptionA nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM; also inhibits PGHS-2 and shows 10-fold selectivity over PGHS-1; exhibits 10-fold selectivity for inhibition of PGHS-2 mediated TxB2 production in a human whole blood assay; Etodolac is licensed for the treatment of inflammation and pain caused by osteoarthritis and rheumatoid arthritis.Pain Approved
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SynonymsAY 24236; (±)-Etodolac; NIH 9918; NSC 282126
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX;RXR-alpha
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Research AreaNeurological Disease
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IndicationPain
Chemical Information
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CAS Number41340-25-4
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Formula Weight287.35
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Molecular FormulaC17H21NO3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(O)CC1(CC)OCCC2=C1NC3=C2C=CC=C3CC
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Chemical NamePyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ito S, et al. J Pharmacol Exp Ther. 2012 Jul;342(1):53-60.
2. Glaser K, et al. Eur J Pharmacol. 1995 Jul 25;281(1):107-11.
3. Suyama H, et al. Brain Res. 2004 Jun 4;1010(1-2):144-50.
2. Glaser K, et al. Eur J Pharmacol. 1995 Jul 25;281(1):107-11.
3. Suyama H, et al. Brain Res. 2004 Jun 4;1010(1-2):144-50.
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