Etodolac

CAS No. 41340-25-4

Etodolac ( AY 24236; (±)-Etodolac; NIH 9918; NSC 282126 )

Catalog No. M14415 CAS No. 41340-25-4

A nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 31 In Stock
50MG 43 In Stock
100MG 61 In Stock
200MG 87 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Etodolac
  • Note
    Research use only, not for human use.
  • Brief Description
    A nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM.
  • Description
    A nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM; also inhibits PGHS-2 and shows 10-fold selectivity over PGHS-1; exhibits 10-fold selectivity for inhibition of PGHS-2 mediated TxB2 production in a human whole blood assay; Etodolac is licensed for the treatment of inflammation and pain caused by osteoarthritis and rheumatoid arthritis.Pain Approved
  • Synonyms
    AY 24236; (±)-Etodolac; NIH 9918; NSC 282126
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX;RXR-alpha
  • Research Area
    Neurological Disease
  • Indication
    Pain

Chemical Information

  • CAS Number
    41340-25-4
  • Formula Weight
    287.35
  • Molecular Formula
    C17H21NO3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(O)CC1(CC)OCCC2=C1NC3=C2C=CC=C3CC
  • Chemical Name
    Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ito S, et al. J Pharmacol Exp Ther. 2012 Jul;342(1):53-60.
2. Glaser K, et al. Eur J Pharmacol. 1995 Jul 25;281(1):107-11.
3. Suyama H, et al. Brain Res. 2004 Jun 4;1010(1-2):144-50.
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